Calcium binds to ______ in banked blood, reducing calcium levels in the blood.

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Multiple Choice

Calcium binds to ______ in banked blood, reducing calcium levels in the blood.

Explanation:
Calcium binds to citrate. Citrate chelates Ca2+, forming calcium citrate, which removes free calcium needed for the coagulation cascade and thus prevents clotting in banked blood. This is why citrate-based anticoagulants like ACD are used in blood storage. Heparin works by enhancing antithrombin III and does not chelate calcium, while EDTA and oxalate chelate calcium but are used in different laboratory contexts, not as the standard banked-blood anticoagulants.

Calcium binds to citrate. Citrate chelates Ca2+, forming calcium citrate, which removes free calcium needed for the coagulation cascade and thus prevents clotting in banked blood. This is why citrate-based anticoagulants like ACD are used in blood storage. Heparin works by enhancing antithrombin III and does not chelate calcium, while EDTA and oxalate chelate calcium but are used in different laboratory contexts, not as the standard banked-blood anticoagulants.

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